Critical Role of Glycogen Synthase Kinase-3β in Regulating the Avian Heterophil Response to Salmonella enterica Serovar Enteritidis

Critical Role of Glycogen Synthase Kinase-3β in Regulating the Avian Heterophil Response to Salmonella enterica Serovar Enteritidis

A microarray-assisted gene expression screen of chicken heterophils revealed glycogen synthase kinase-3β (GSK-3β), a multifunctional Ser/Thr kinase, to be consistently upregulated 30-180 min following stimulation with Salmonella enterica serovar Enteritidis (S. Enteritidis). The present study was designed to delineate the role of GSK-3β in regulating the innate function of chicken heterophils i...

Salmonella enterica Serovar Enteritidis, Japan

To the Editor: Nontyphoidal sal-monellae are the important causative agents of foodborne diseases in Japan and other industrialized countries. Salmonella enterica serovar Enter-itidis has risen to the leading cause of infection among Salmonella spp. since 1989 (1). Emergence of drug-resistant S. Enteritidis has been rarely reported while S. Typhimurium, another serovar of major public health co...

Immunoprotectivity of Salmonella enterica serovar Enteritidis virulence protein, InvH, against Salmonella typhi

Objective(s):Typhoid fever is a dreadful disease of a major threat to public health in developing countries. Vaccination with bacterial immunodominant components such as surface proteins may prove as a potent alternative to live attenuated vaccines. InvH, an important part of needle complex in type three secretion system (TTSS) plays important role in efficient bacterial adherence and entry int...

Virulence factors of Salmonella enterica serovar Enteritidis

Occurrence of multidrug-resistant Salmonella enterica serovar Enteritidis isolates from poultry in Iran

Salmonella enterica is recognized as one of the major food-borne pathogens with more than 2,500 serotypesworldwide. The present study addresses antimicrobial resistance of Salmonella enterica serovar Enteritidisisolates in Iran. A collection of 151 Salmonella spp. isolates collected from poultry were serotyped toidentify Salmonella Enteritidis. Sixty-one Salmonella Enteritidis were subsequently...